Long, loooong, or looooooooooooooooong?
If it's the latter, you might be interested in
this topic. I haven't looked at all of them and most of them require doing other things than waiting, but if you want to create something ridiculously long, the method of choice seems to be a binary counter.
I've gotten curious after reading your post, and the
5.1 5.x engine allows for some pretty cool optimizations. I've found a pretty space-saving mechanism with roach queens / force arrows / pressure plates / fire traps. Note that I haven't done all the pp connections yet, because, let's face it, that's almost as boring as solving the room. However, if I were to do so, this room should take over 10^75 moves to complete. Ctrl+5 allows you to pass about 7000 moves per minute, but even so, this would result in waiting for over 10^65 years. In your face, Doctor!
(Note that, because I was so lazy, the room isn't currently solvable, but the concept should be clear)
If you just want annoying but realistic amounts of wait, your suggestions seem fine to me. Briar is another idea that comes to mind.
[Last edited by Lucky Luc at 03-07-2016 01:16 PM]