What's catching you at the very end?
If it's a tar or mud baby:
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×Have Beethro and the briar get rid of these before he steps up into Row 4 (when the spiders attack). It helps if Beethro attacks the outside mud blobs as he moves through the room. This reduces the number of babies that he has to fight when the briar grows. Try to make Beethro move in a general upward direction as he fights, rather than swing his sword. If need be, (12,13) is a safe place for fighting off a wave of babies.
If the briar catches you when you're fighting the spiders:
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×Don't let the spiders stop Beethro in a dangerous spot. When fighting the spiders, start in Row 4, and kill them by moving east. Just before the dropped blue door, he can step up to squares (30,3) and (30,2) and finish them off. The orb stops briar growth, but you should not need to use it.
Hope this helps