Serpents do not move diagonally, so you can do a bit of dodging when in open areas.
× When left alone, they will change directions every five turns, either going horizontally or vertically, so serpents normally move in loops if you aren't angering them.
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× Well, unless you are standing in front of them, in which case they will head straight for you, regardless of turns. Serpents can see from across the room for this purpose.
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× If you are behind them, it will still affect their movement.