Initially, I was going to ask how to clear enough space to reach the potion without causing the briar to close off the ways out. As is often the case with these magical forums, I realized my own answer as soon as I started typing:
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×Kill the Seep near the entry, the one you can reach without crossing Oremites. Cross the 'mites, then kill one of the two Seep around the next corner and you have a free path to the potion. Just leave the way you came.
However, the urge for completeness now makes me wish for a means of killing all the remaining Seep in this room. Problem is, with the Oremites all around, I can't bring in Briar Hacker to trim the weeds back after every couple kills.
Any means of wiping out the Seep, or am I doomed to be annoyed by letting them live?
(At least it's not a room full of Wubbas. I have HATED those things since the first DROD I played)