Here are some interesting tips no one has yet mentioned. No guarantees they will get you a high score, though.
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×It is easier to beat this room if you do not kill all the small snakes first.
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×Watch the wisp carefully.
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×This wisp cab be interrupted fairly easily.
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×Such as by a snake that cuts its path.
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×So if you leave a bunch of snakes behind you, the slayer will virtually never move as the wisp path will be cut so often.
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×This gives you time to deal with the long snake and golems without being too pressured.
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×It's relatively easy to build a snake trap with golems.
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×One snake trap is a square where three orthagonal neighbors are blocked with walls or dead golems. (Diagonals don't matter for snake traps.)
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×You could even build a snake trap with a single dead golem where the wall is diagonal.
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×When trapping a long snake, make sure you can move where you need to go, such as its tail.
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×Once you trap the long snake, kill the rest of the golems, then kill the trapped long snake, then kill the rest of the wandering small snakes and head for the exit.